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6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide(CAS: 58-93-5)

6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
CAS Number

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Basic Information

Molecular Formula
C7H8ClN3O4S2
Molecular Weight
297.75 g/mol

Physical Properties

Melting Point
273-275 ºC
Boiling Point
577°Cat760mmHg

Chemical Identifiers

SMILES
NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl
InChIKey
JZUFKLXOESDKRF-UHFFFAOYSA-N

Database References

MDL Number
MFCD00051765
Beilstein Registry Number
625101

FAQ

6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide (CAS: 58-93-5) is a sulfonamide derivative with the chemical formula C8H8ClN3O4S2. It is a white crystalline solid, known for its stability and solubility in polar solvents. The compound features a benzothiadiazine ring with a sulfonamide group and a dioxide functional group, making it a key intermediate in pharmaceutical synthesis. Its molecular structure contributes to its use in medicinal chemistry due to its ability to modulate enzyme activity.
6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide (CAS: 58-93-5) is primarily used in pharmaceuticals as an active ingredient in antihypertensive drugs like losartan. It also serves as a chemical intermediate in the production of other medicinal compounds and pesticide formulations. In research, it is employed for studying enzyme inhibition mechanisms. Its applications span across drug development, industrial chemistry, and agricultural science.
6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide (CAS: 58-93-5) is generally safe when handled according to standard safety protocols. It has a low toxicity profile but requires caution during handling to avoid skin and eye contact. Safety guidelines recommend using protective equipment, such as gloves and goggles, and working in a well-ventilated area. Proper storage is essential to maintain its stability and ensure safety in industrial and research settings.
6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide (CAS: 58-93-5) should be stored in a cool, dry place at 20-25°C, away from light and moisture. It is best kept in airtight, dark-colored containers to prevent degradation. Avoid exposure to heat sources and maintain low humidity levels to ensure stability. Storage conditions must adhere to safety standards to preserve its chemical integrity and effectiveness for pharmaceutical and industrial use.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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Zhu Fangran

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