Methyl 4-(aminomethyl)-3-chlorobenzoate(CAS: 940062-11-3)

Methyl 4-(aminomethyl)-3-chlorobenzoate (CAS: 940062-11-3) is a crystalline compound with a molecular weight of approximately 229.58 g/mol. It has a solubility of about 1.2 g/100 mL in water and a high solubility in organic solvents such as DMF and DMSO. The compound is moderately reactive, particularly toward nucleophilic substitution and amine reactions. It is stable under normal ambient conditions but should be stored in a cool, dry place away from strong acids and bases.

Methyl 4-(aminomethyl)-3-chlorobenzoate (CAS: 940062-11-3) is typically synthesized through a reaction of 3-chlorobenzoic acid with methylamine followed by esterification. The synthesis involves condensation of 3-chlorobenzoic acid with methylamine to form the amide, which is then esterified with methanol in the presence of a catalyst like sulfuric acid. The yield is typically around 85-90%, with good selectivity towards the desired product.

Methyl 4-(aminomethyl)-3-chlorobenzoate (CAS: 940062-11-3) is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those requiring specific functional groups or structural motifs. It is also used in the polymer industry as a monomer for the development of novel materials with specific properties. Additionally, it has applications in the production of sensors and semiconductors due to its unique chemical properties.

When handling Methyl 4-(aminomethyl)-3-chlorobenzoate (CAS: 940062-11-3), it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a fume hood to minimize exposure to vapors. Spills should be cleaned up carefully using appropriate absorbent materials, and the area should be well-ventilated. For more detailed safety information, refer to the Material Safety Data Sheet (SDS) for this compound.