2,4,6-Trichloro-5-methoxypyrimidine(CAS: 60703-46-0)

2,4,6-Trichloro-5-methoxypyrimidine (CAS: 60703-46-0) is a crystalline solid with a molecular weight of approximately 265.02 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is moderately reactive, particularly towards nucleophiles. It decomposes at temperatures above 200°C and should be handled with caution due to its potential to release toxic gases upon decomposition.

2,4,6-Trichloro-5-methoxypyrimidine (CAS: 60703-46-0) is commonly synthesized by the reaction of 2,4,6-trichloropyrimidin-5-yl chloride with methanol in the presence of a base such as sodium hydride. The reaction typically yields a high purity product with good selectivity and high yield. Common solvents used include dimethylformamide (DMF) or dimethyl sulfoxide (DMSO).

2,4,6-Trichloro-5-methoxypyrimidine (CAS: 60703-46-0) is used in various industries including pharmaceuticals, where it serves as a precursor in the synthesis of medicinal compounds; in polymer science, where it can be used as a monomer or additive; and in the electronics industry, where it may be utilized in semiconductors or sensors due to its chemical stability and reactivity.

When handling 2,4,6-Trichloro-5-methoxypyrimidine (CAS: 60703-46-0), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure to toxic gases. Spills should be cleaned up carefully using appropriate absorbent materials and disposed of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling and disposal information.