ethyl 5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)piperazin-1-yl)benzofuran-2-carboxylate (dihydrochloride)(CAS: 163521-09-3)

Ethyl 5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)piperazin-1-yl)benzofuran-2-carboxylate (dihydrochloride) is a crystalline compound with a molecular weight of approximately 654.3 g/mol. It has good solubility in water and organic solvents. The compound is moderately reactive and prone to hydrolysis under acidic conditions. It is stable under normal laboratory conditions but should be handled with care to avoid direct contact and moisture exposure.

Ethyl 5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)piperazin-1-yl)benzofuran-2-carboxylate (dihydrochloride) is synthesized via a multi-step process involving coupling reactions and final hydrochloridation. The synthesis involves the use of a palladium catalyst and requires high purity reagents. The yield is typically 70-80%, and the product is isolated by recrystallization from ethanol.

Ethyl 5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)piperazin-1-yl)benzofuran-2-carboxylate (dihydrochloride) is primarily used in the pharmaceutical industry for its potential as an intermediate in drug synthesis. It may also find applications in the polymer industry for specific functional polymer modifications and in sensor technology for its unique chemical structure.

When handling ethyl 5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)piperazin-1-yl)benzofuran-2-carboxylate (dihydrochloride), it is essential to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat to avoid direct contact. Handle in a well-ventilated fume hood to minimize inhalation risks. Spills should be cleaned up with caution, using absorbent materials, and the area should be thoroughly washed down. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions.