8-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)quinolin-2(1H)-one(CAS: 147568-66-9)

8-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)quinolin-2(1H)-one is a crystalline solid with a molecular weight of approximately 454.4 g/mol. It is poorly soluble in water but soluble in organic solvents like DMSO and acetonitrile. The compound has moderate reactivity, particularly with bases and reducing agents. It can undergo hydrolysis and deamination under acidic conditions.

The compound is typically synthesized via multi-step organic synthesis, involving the coupling of a quinoline derivative with an amino acid derivative. The synthesis involves the use of protecting groups and various catalysts such as Pd(CP)2Cl2 for coupling reactions. The overall yield is around 70%, with high selectivity towards the desired product.

This compound is primarily used in the pharmaceutical industry for its potential as an active pharmaceutical ingredient (API) due to its pharmacological properties. It is also of interest in the research of specific biochemical pathways and molecular targets. Limited applications exist in polymer and sensor industries, but its use is primarily driven by its unique chemical structure and potential biomedical applications.

When handling 8-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)quinolin-2(1H)-one, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risk. Spills should be cleaned up immediately following proper safety protocols, and the material safety data sheet (MSDS) should be consulted for detailed safety information.