Compound Q&A

How is 8-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)quinolin-2(1H)-one (CAS: 147568-66-9) typically synthesized?

Answer

8-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)quinolin-2(1H)-one
The compound is typically synthesized via multi-step organic synthesis, involving the coupling of a quinoline derivative with an amino acid derivative. The synthesis involves the use of protecting groups and various catalysts such as Pd(CP)2Cl2 for coupling reactions. The overall yield is around 70%, with high selectivity towards the desired product.

About

English Name 8-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)quinolin-2(1H)-one
Molecular Formula C21H24N2O4
Molecular Weight 368.4 g/mol
SMILES CC(CC1=CC=C(C=C1)OC)NCC(C2=C3C=CC(=O)NC3=C(C=C2)O)O
InChIKey IHOXNOQMRZISPV-YJYMSZOUSA-N
Last Updated: 2026-01-01 01:49

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