N-[(4-Methoxyphenyl)sulfonyl]-N-{2-[(E)-2-(1-oxido-4-pyridinyl)vinyl]phenyl}acetamide(CAS: 173529-46-9)

N-[(4-Methoxyphenyl)sulfonyl]-N-{2-[(E)-2-(1-oxido-4-pyridinyl)vinyl]phenyl}acetamide, CAS 173529-46-9, is a white crystalline solid with a molecular weight of approximately 549.4 g/mol. It is slightly soluble in organic solvents like methanol and acetonitrile but insoluble in water. This compound is known for its high stability and reactivity in various chemical reactions, particularly in nucleophilic substitution and condensation reactions.

N-[(4-Methoxyphenyl)sulfonyl]-N-{2-[(E)-2-(1-oxido-4-pyridinyl)vinyl]phenyl}acetamide is synthesized through a multi-step process involving the coupling of a 4-pyridinyl vinyl ketone and a sulfonyl chloride derivative. This reaction is catalyzed by a transition metal like palladium, with a high yield and good selectivity, making it suitable for industrial production.

N-[(4-Methoxyphenyl)sulfonyl]-N-{2-[(E)-2-(1-oxido-4-pyridinyl)vinyl]phenyl}acetamide is primarily used in the pharmaceutical industry for the development of new drugs due to its unique chemical structure. It is also explored in sensor technology and semiconductor applications for its specific reactivity and stability.

When handling N-[(4-Methoxyphenyl)sulfonyl]-N-{2-[(E)-2-(1-oxido-4-pyridinyl)vinyl]phenyl}acetamide, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, safety glasses, and a lab coat. This compound should be used in a well-ventilated area or a fume hood to minimize inhalation risk. In case of a spill, ensure the area is well-ventilated and clean up using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed instructions.