N-{3-[(2-Cyanoethyl)(ethyl)amino]-4-methoxyphenyl}acetamide(CAS: 19433-94-4)

N-{3-[(2-Cyanoethyl)(ethyl)amino]-4-methoxyphenyl}acetamide is a white or off-white crystalline solid with a molecular weight of approximately 364.39 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and dimethylformamide. The compound is moderately reactive, showing some basic properties due to the amine group and can undergo nucleophilic substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place away from strong acids and bases.

N-{3-[(2-Cyanoethyl)(ethyl)amino]-4-methoxyphenyl}acetamide is typically synthesized via a multi-step process involving the reaction of 4-methoxyaniline with 2-(ethoxycarbonylamino)ethyl cyanide followed by acetylation. The synthesis begins with the formation of an intermediate amide, which is then acetylated using acetic anhydride or acetyl chloride. The yield is generally around 70-80%, and the reaction is catalyzed by a suitable base such as triethylamine.

N-{3-[(2-Cyanoethyl)(ethyl)amino]-4-methoxyphenyl}acetamide is used in several industries due to its chemical properties. It is primarily used in pharmaceuticals for its potential as a drug intermediate. It also finds applications in the synthesis of polymer compounds, sensors, and semiconductors, particularly in the development of novel materials with specific functional properties.

When handling N-{3-[(2-Cyanoethyl)(ethyl)amino]-4-methoxyphenyl}acetamide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a fume hood to minimize exposure to vapors. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Safety data sheets (SDS) should be consulted for detailed information on handling, storage, and emergency procedures. Storage should be in a cool, dry place, away from strong acids and bases.