3-Amino-1H-indazol-4-ol(CAS: 88805-68-9)

3-Amino-1H-indazol-4-ol (CAS: 88805-68-9) is a white crystalline solid. It has a molecular weight of approximately 166.18 g/mol. The compound is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. It is moderately reactive, showing good stability under neutral conditions but can undergo hydrolysis in acidic or basic environments.

3-Amino-1H-indazol-4-ol is typically synthesized through amination of 1H-indazol-4-one with ammonia or an amine derivative. Common methods include the use of potassium hydroxide in ethanol as a base, with a yield of about 70-80%. The reaction is selective and proceeds at room temperature under mild conditions.

3-Amino-1H-indazol-4-ol (CAS: 88805-68-9) finds applications in the pharmaceutical industry, particularly in the synthesis of various drug candidates. It is also used in the development of sensors and as a precursor in the production of certain polymers and semiconductors due to its functional groups and chemical reactivity.

When handling 3-Amino-1H-indazol-4-ol (CAS: 88805-68-9), it is essential to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed emergency procedures and storage guidelines.