4-Chloro-1,5-naphthyridine(CAS: 7689-63-6)

4-Chloro-1,5-naphthyridine is a crystalline compound with a molecular weight of 183.02 g/mol. It has a low solubility in water but good solubility in organic solvents. The compound shows moderate reactivity, particularly towards nucleophiles and bases, making it suitable for various synthetic transformations.

4-Chloro-1,5-naphthyridine is commonly synthesized through the chlorination of 1,5-naphthyridine using thionyl chloride. The process involves the addition of thionyl chloride to a solution of 1,5-naphthyridine in an appropriate solvent, followed by heating to promote the chlorination reaction.

4-Chloro-1,5-naphthyridine finds applications in the pharmaceutical industry, where it serves as a precursor for drug synthesis. It is also used in the chemical industry for the production of dyes and other organic compounds. Additionally, it is used in the polymer industry as a stabilizer and in the development of sensors.

When handling 4-Chloro-1,5-naphthyridine, protective equipment such as gloves, goggles, and a lab coat should be worn. The compound should be stored in a closed container and handled in a well-ventilated area or a fume hood. In case of a spill, immediately clean up the area and refer to the Safety Data Sheet (SDS) for detailed spill management instructions.