Glycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucyl-L-glutamine(CAS: 113274-56-9)

Glycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucyl-L-glutamine is a complex peptide with a molecular weight of approximately 1475.6 g/mol. It is highly soluble in water and slightly soluble in ethanol. It exhibits moderate reactivity, particularly with nucleophiles. This peptide is stable under mild conditions but can be vulnerable to proteolytic degradation under harsh conditions. It crystallizes in a form that is stable under room temperature conditions.

Glycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucyl-L-glutamine is synthesized through solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The synthesis involves sequential coupling of protected amino acids, followed by cleavage from the resin and purification. The final product is obtained with good yield and high purity, typically using HPLC for purification.

Glycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucyl-L-glutamine is primarily used in the pharmaceutical industry for the development of peptides and proteins. It is also utilized in the polymer industry for the modification of polymer properties, in sensor technology for detecting specific biological markers, and in semiconductor applications for specific functional groups.

When handling Glycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucyl-L-glutamine, it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. In case of a spill, immediately clean up using appropriate absorbent materials and dispose of waste according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling and emergency instructions.