Compound Q&A
How is Glycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucyl-L-glutamine (CAS: 113274-56-9) typically synthesized?
Answer
Glycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucyl-L-glutamine is synthesized through solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The synthesis involves sequential coupling of protected amino acids, followed by cleavage from the resin and purification. The final product is obtained with good yield and high purity, typically using HPLC for purification.
About
CAS No
113274-56-9
English Name
Glycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucyl-L-glutamine
Molecular Formula
C66H93N13O25
Molecular Weight
1468.5360000000007 g/mol
SMILES
CCC(C)C(C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CC(=O)O)NC(=O)CN
InChIKey
ZNEKMMIWGPUTGR-SQJOKQRMSA-N
Last Updated: 2025-09-09 19:18
