2-Methyl-2-propanyl methyl[(3R)-3-pyrrolidinyl]carbamate(CAS: 392338-15-7)

2-Methyl-2-propanyl methyl[(3R)-3-pyrrolidinyl]carbamate is a colorless or white crystalline solid with a molecular weight of approximately 265.43 g/mol. It has a pKa of about 8.5 and a solubility of about 10 g/L in water. This compound is moderately reactive and susceptible to hydrolysis in acidic and basic conditions.

2-Methyl-2-propanyl methyl[(3R)-3-pyrrolidinyl]carbamate is typically synthesized by the reaction between 2-methyl-2-propanol and methyl (3R)-3-pyrrolidinyl carbamate in the presence of a catalytic amount of a strong base such as sodium hydride. The yield is approximately 85-90%, and the reaction is carried out at room temperature.

2-Methyl-2-proanyl methyl[(3R)-3-pyrrolidinyl]carbamate is used in the pharmaceutical and chemical industries for its potential as a bioisostere in drug design. It is also utilized in the development of sensors and as a building block in organic synthesis.

When handling 2-Methyl-2-proanyl methyl[(3R)-3-pyrrolidinyl]carbamate, wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Store the compound in a cool, dry place away from direct sunlight. In case of a spill, clean up immediately using appropriate methods and consult the Safety Data Sheet (SDS) for detailed instructions.