4-Methoxy-N-phenylaniline(CAS: 1208-86-2)

4-Methoxy-N-phenylaniline (CAS: 1208-86-2) is a white crystalline solid with a molecular weight of approximately 194.21 g/mol. It has a melting point of 59-61°C and is slightly soluble in water. Chemically, it is less reactive than its parent compound but can undergo electrophilic aromatic substitution reactions. It is insoluble in most common organic solvents, making it useful for certain purification and synthesis steps.

4-Methoxy-N-phenylaniline is typically synthesized from p-aminophenol and methanol via a methylation reaction, often using a strong acid like sulfuric acid as a catalyst. The reaction selectively methylates the ortho-position, producing a high yield of 4-methoxy-N-phenylaniline. This method is efficient and widely used in the chemical industry.

4-Methoxy-N-phenylaniline (CAS: 1208-86-2) is primarily used in the pharmaceutical industry as a precursor for the synthesis of certain drugs. It is also utilized in the production of organic pigments, dyes, and other organic chemicals. Additionally, it finds applications in the development of sensors and semiconductors due to its chemical reactivity.

When handling 4-Methoxy-N-phenylaniline (CAS: 1208-86-2), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Store it in a cool, dry place, away from heat and direct sunlight. In case of a spill, use appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for disposal. Always work in a well-ventilated area or fume hood to minimize exposure to vapors.