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O-(2-Methyl-2-propanyl)threonine(CAS: 4378-13-6)

O-(2-Methyl-2-propanyl)threonine
CAS Number

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Basic Information

Molecular Formula
C8H17NO3
Molecular Weight
175.23 g/mol

Physical Properties

Melting Point
260°C(dec.)(lit.)
Boiling Point
275 ºC
Flash Point
120 ºC

Chemical Identifiers

SMILES
CC(C(C(=O)O)N)OC(C)(C)C
InChIKey
NMJINEMBBQVPGY-RITPCOANSA-N

Database References

MDL Number
MFCD00037766

FAQ

O-(2-Methyl-2-propanyl)threonine (CAS: 4378-13-6) is a white crystalline powder with a molecular weight of approximately 184.3 g/mol. It has a low water solubility and is slightly soluble in ethanol. The compound is reactive towards bases and can undergo hydrolysis under basic conditions. It is insoluble in water but soluble in organic solvents such as methanol and acetone.
O-(2-Methyl-2-propanyl)threonine (CAS: 4378-13-6) can be synthesized via a multi-step process involving the condensation of threonine with 2-methyl-2-propanol in the presence of a Lewis acid catalyst such as aluminum chloride. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity. Post-synthesis purification involves recrystallization from ethanol to obtain pure product.
O-(2-Methyl-2-propanyl)threonine (CAS: 4378-13-6) is used in the pharmaceutical industry as a precursor for the synthesis of certain pharmaceuticals due to its structural similarity to threonine. It also finds applications in the production of polymers, where it can serve as a monomer, and in the development of sensors and semiconductors due to its unique chemical properties.
When handling O-(2-Methyl-2-proanyl)threonine (CAS: 4378-13-6), it is important to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of spill, immediately clean up using proper absorbent material and dispose of waste according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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