Compound Q&A

How is O-(2-Methyl-2-propanyl)threonine (CAS: 4378-13-6) typically synthesized?

Answer

O-(2-Methyl-2-propanyl)threonine
O-(2-Methyl-2-propanyl)threonine (CAS: 4378-13-6) can be synthesized via a multi-step process involving the condensation of threonine with 2-methyl-2-propanol in the presence of a Lewis acid catalyst such as aluminum chloride. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity. Post-synthesis purification involves recrystallization from ethanol to obtain pure product.

About

CAS No 4378-13-6
English Name O-(2-Methyl-2-propanyl)threonine
Molecular Formula C8H17NO3
Molecular Weight 175.22799999999995 g/mol
SMILES CC(C(C(=O)O)N)OC(C)(C)C
InChIKey NMJINEMBBQVPGY-RITPCOANSA-N
Last Updated: 2025-09-13 09:53

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