2-Ethoxy Benzamidine Hydrochloride(CAS: 18637-00-8)

2-Ethoxy Benzamidine Hydrochloride is a white to off-white crystalline solid. Its molecular weight is approximately 257.8 g/mol. The compound is slightly soluble in water and ethanol. It is relatively stable under normal conditions but may react with strong bases. It has a pKa of about 8.6.

2-Ethoxy Benzamidine Hydrochloride is typically synthesized by a multi-step process involving the reaction of ethoxybenzene with benzamide followed by the addition of hydrochloric acid. The key steps include the preparation of the amide and subsequent quaternization to form the ethoxy derivative. The reaction is carried out under basic conditions and the product is isolated by recrystallization.

2-Ethoxy Benzamidine Hydrochloride is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It is also utilized in the production of some agricultural chemicals. Additionally, it can be used in the synthesis of other organic compounds and as a reagent in organic chemistry research.

When handling 2-Ethoxy Benzamidine Hydrochloride, it is important to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat to protect against skin and eye contact. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation. Spills should be carefully cleaned up using appropriate procedures, and the material safety data sheet (MSDS) should be consulted for detailed guidance on safe handling and disposal.