2-{4-[(E)-(2-Oxocyclohexylidene)methyl]phenyl}propanoic acid(CAS: 69956-77-0)

2-{4-[(E)-(2-Oxocyclohexylidene)methyl]phenyl}propanoic acid has a crystalline form with a molecular weight of approximately 310.45 g/mol. It has a limited solubility in water and a higher solubility in organic solvents like ethanol and acetone. The compound is relatively stable under normal conditions but can undergo hydrolysis in strongly acidic or basic media. It is reactive towards nucleophiles and can participate in condensation reactions.

2-{4-[(E)-(2-Oxocyclohexylidene)methyl]phenyl}propanoic acid is synthesized via a multi-step process that involves the condensation of 2-cyclohexenone and 4-bromobenzoic acid, followed by acid-catalyzed hydrolysis. The reaction typically requires a mild base catalyst and proceeds with high selectivity and moderate to good yield.

2-{4-[(E)-(2-Oxocyclohexylidene)methyl]phenyl}propanoic acid is utilized in the pharmaceutical industry for the synthesis of certain drugs. It is also employed in the polymer industry as a monomer for the production of special polymers. Additionally, it has potential applications in the development of sensors and semiconductors.

When handling 2-{4-[(E)-(2-Oxocyclohexylidene)methyl]phenyl}propanoic acid, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a cool, dry place away from heat sources and strong acids or bases. In case of a spill, use appropriate absorbent materials and follow local safety regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.