[2-(1H-Pyrazol-1-yl)phenyl]methanol(CAS: 741717-59-9)

[2-(1H-Pyrazol-1-yl)phenyl]methanol (CAS: 741717-59-9) is a white crystalline solid with a molecular weight of approximately 216.22 g/mol. It is slightly soluble in water but soluble in common organic solvents such as ethanol and acetonitrile. It has a moderate reactivity, particularly with acids and bases. The compound can undergo substitution and ring-opening reactions under specific conditions.

[2-(1H-Pyrazol-1-yl)phenyl]methanol (CAS: 741717-59-9) can be synthesized via a multistep process starting from 2-chlorophenol and pyrazole. The reaction involves the coupling of 2-chlorophenol with pyrazole under basic conditions, followed by reduction of the resulting chlorophenyl group to a hydroxyl group. Common catalysts include palladium(II) acetate with triphenylphosphine, and the overall yield is around 70-80%.

[2-(1H-Pyrazol-1-yl)phenyl]methanol (CAS: 741717-59-9) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of drugs. It also has potential applications in the polymer field for the development of new materials with enhanced properties. Additionally, it can be utilized in the production of sensors and semiconductors due to its unique chemical properties.

Proper handling of [2-(1H-Pyrazol-1-yl)phenyl]methanol (CAS: 741717-59-9) requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of spills, handle with care using a spill kit and follow safety data sheet (SDS) guidelines for disposal. Always perform experiments in a fume hood to minimize exposure to the compound.