2-O-Acetyl-1,4:3,6-dianhydro-D-glucitol(CAS: 13042-39-2)

2-O-Acetyl-1,4:3,6-dianhydro-D-glucitol is a white crystalline solid with a molecular weight of approximately 216.24 g/mol. It is slightly soluble in water and ethanol. Chemically, it is less reactive than its parent compound, glucose, due to the acetyl group substitution and the presence of the anhydro ring, which makes it more stable and less prone to hydrolysis.

2-O-Acetyl-1,4:3,6-dianhydro-D-glucitol is typically synthesized by the acetylation of 1,4:3,6-dianhydro-D-glucitol using acetic anhydride in the presence of an acidic catalyst under mild conditions. This process provides good yield and selectivity, making it a viable method for industrial production.

2-O-Acetyl-1,4:3,6-dianhydro-D-glucitol is used in the pharmaceutical industry as a precursor for the synthesis of pharmaceutical intermediates, in the polymer industry for the production of specialized polymers, and in the sensor industry for its unique physicochemical properties.

When handling 2-O-Acetyl-1,4:3,6-dianhydro-D-glucitol, it is recommended to work in a fume hood. Use appropriate personal protective equipment (PPE) such as gloves and goggles. Spills should be cleaned up with dry absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.