6-Fluoro-3-iodoimidazo[1,2-a]pyridine(CAS: 1219127-01-1)

6-Fluoro-3-iodoimidazo[1,2-a]pyridine (CAS: 1219127-01-1) is a crystalline solid with a molecular weight of approximately 258.04 g/mol. It is poorly soluble in water but soluble in organic solvents like dimethylformamide (DMF) and acetonitrile. The compound is known for its high reactivity, particularly towards nucleophiles and electrophiles, and it is often used in medicinal chemistry for its pharmacological potential.

6-Fluoro-3-iodoimidazo[1,2-a]pyridine (CAS: 1219127-01-1) is usually synthesized via the iodination of 6-fluorimidazo[1,2-a]pyridine using N-iodosuccinimide (NIS) in the presence of a palladium catalyst. The reaction involves a Suzuki-Miyaura coupling and typically yields a high purity product with good selectivity and yield under optimized conditions.

6-Fluoro-3-iodoimidazo[1,2-a]pyridine (CAS: 1219127-01-1) is primarily used in the pharmaceutical industry for drug development, particularly in the synthesis of novel antitumor and antiviral agents. It also finds applications in semiconductor manufacturing as a precursor for the production of functional materials with unique electronic properties.

When handling 6-Fluoro-3-iodoimidazo[1,2-a]pyridine (CAS: 1219127-01-1), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The substance should be used in a well-ventilated area or a fume hood to prevent inhalation of fumes. Spills should be handled with caution, and the material safety data sheet (MSDS) should be consulted for detailed spill cleanup procedures. Storage should be in a cool, dry place away from direct sunlight and flammable materials.