Aciclovir (Acyclovir) EP Impurity M(CAS: 91702-60-2)

Aciclovir EP Impurity M is a white to off-white crystalline powder with a molecular weight of approximately 226.22 g/mol. It has a solubility of about 50 mg/mL in water and is relatively stable under normal storage conditions. Aciclovir EP Impurity M is reactive towards nucleophilic substitution and can form amides under certain conditions.

Aciclovir EP Impurity M is typically synthesized through a series of chemical reactions, including nucleophilic substitution and condensation. The key steps involve the preparation of an acyclic intermediate, which is then further modified to form the desired impurity. Common catalysts and reagents include acyl chlorides, amines, and hydroxylamine derivatives. The overall yield is approximately 70-80%.

Aciclovir EP Impurity M is primarily used in the pharmaceutical industry as an intermediate in the synthesis of aciclovir, a broad-spectrum antiviral drug. It is also of interest in academic and industrial research for its potential applications in developing new antiviral agents and drug delivery systems.

When handling Aciclovir EP Impurity M (CAS: 91702-60-2), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a well-ventilated area or fume hood to minimize exposure. In case of a spill, it should be carefully cleaned up according to the Safety Data Sheet (SDS). Always consult the SDS for specific handling and disposal instructions.