2-Methyl-2-phenylpropanenitrile(CAS: 1195-98-8)

2-Methyl-2-phenylpropanenitrile (CAS: 1195-98-8) is a colorless to light yellow liquid with a molecular weight of approximately 154.23 g/mol. It is slightly soluble in water but miscible with organic solvents. Chemically, it is relatively stable but can react with strong oxidizers. It has a relatively low boiling point of 109-110°C and a melting point of -48°C to -47°C.

2-Methyl-2-phenylpropanenitrile (CAS: 1195-98-8) is usually synthesized via a nitrile addition reaction, where an alkyl nitrile reacts with a phenylacetylene. Common methods include the use of palladium catalysts in the presence of a base, leading to a high yield of the desired product with good selectivity.

2-Methyl-2-phenylpropanenitrile (CAS: 1195-98-8) is employed in various industries. It is used as a precursor in pharmaceutical manufacturing, where it serves as an intermediate for drug synthesis. It also finds applications in polymer chemistry for developing specialized polymers, and in the sensor industry for its potential as a chemical sensor material.

When handling 2-Methyl-2-phenylpropanenitrile (CAS: 1195-98-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Operations should be conducted in a well-ventilated area or a fume hood. Spills should be handled promptly with absorbent materials, and the chemical should be stored in a cool, dry place away from heat sources. Always refer to the Safety Data Sheet (SDS) for detailed safety guidelines.