2-Chloro-6-methoxypyridine(CAS: 17228-64-7)

2-Chloro-6-methoxypyridine (CAS: 17228-64-7) is a crystalline solid with a molecular weight of approximately 185.62 g/mol. It is slightly soluble in water but soluble in common organic solvents like ethanol and acetone. The compound is reactive, particularly towards nucleophiles, and can undergo substitution reactions. It has a melting point around 117-118°C.

2-Chloro-6-methoxypyridine (CAS: 17228-64-7) can be synthesized via the reaction of chloromethylbenzene with methanol in the presence of a suitable acid catalyst, such as sulfuric acid. The reaction typically proceeds with good yield and selectivity, producing the 2-chloro-6-methoxypyridine product.

2-Chloro-6-methoxypyridine (CAS: 17228-64-7) is mainly used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also used in the chemical industry for the production of dyes, polymers, and other organic compounds. Additionally, it has applications in the sensor and semiconductor industries.

When handling 2-Chloro-6-methoxypyridine (CAS: 17228-64-7), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a well-ventilated area and handled in a fume hood to avoid inhalation and skin contact. In case of a spill, it should be cleaned up carefully following safety procedures and using appropriate materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information.