1-(3,4-Dichlorophenyl)-1-propanone(CAS: 6582-42-9)

1-(3,4-Dichlorophenyl)-1-propanone (CAS: 6582-42-9) is a crystalline compound with a molecular weight of approximately 219.03 g/mol. It has a high melting point of 86-88°C and is poorly soluble in water but soluble in organic solvents like ethanol and acetone. The compound is known for its moderate reactivity, particularly in electrophilic aromatic substitution reactions. It is used in the synthesis of various pharmaceuticals and polymers.

1-(3,4-Dichlorophenyl)-1-propanone (CAS: 6582-42-9) can be synthesized via the acylation of 3,4-dichlorophenol with propanoyl chloride in the presence of a strong acid catalyst, such as sulfuric acid. The reaction is carried out at room temperature, and the product can be isolated by recrystallization. The yield is typically around 85-90%, and the reaction is highly selective for the desired product.

1-(3,4-Dichlorophenyl)-1-propanone (CAS: 6582-42-9) is primarily used in the pharmaceutical and polymer industries. It serves as a precursor in the synthesis of various drugs and is also used in the production of certain polymers due to its reactivity and stability. Additionally, it finds applications in the chemical sensing industry for the development of gas sensors.

When handling 1-(3,4-Dichlorophenyl)-1-propanone (CAS: 6582-42-9), appropriate personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. The compound should be stored in a well-ventilated area and handled under a fume hood to avoid inhalation. In case of a spill, ensure proper containment and clean up using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.