Ethyl N-(diphenylmethylene)-4-methylenenorvalinate(CAS: 80741-44-2)

Ethyl N-(diphenylmethylene)-4-methylenenorvalinate is a crystalline compound with a molecular weight of approximately 368.3 g/mol. It has a low solubility in water but is soluble in common organic solvents like ethanol and acetone. The compound exhibits moderate reactivity, particularly in ester hydrolysis. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

Ethyl N-(diphenylmethylene)-4-methylenenorvalinate is typically synthesized via esterification of diphenylmethylene-4-methyleneacetic acid with ethyl alcohol. Commonly, this reaction is catalyzed by a strong acid like sulfuric acid at moderate temperatures. The yield is generally high, and the reaction is selective, producing the desired ester with minimal by-products.

Ethyl N-(diphenylmethylene)-4-methylenenorvalinate is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the polymer industry for modifying polymer properties and in the chemical sensor industry for specific chemical detection applications.

Proper personal protective equipment (PPE) should be worn when handling this compound, including gloves and safety glasses. Storage should be in a cool, dry place away from heat and direct sunlight. Spills should be cleaned up using appropriate absorbents, and the area should be well-ventilated. For detailed safety information, refer to the Safety Data Sheet (SDS).