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2-(Trifluoromethyl)benzohydrazide(CAS: 344-95-6)

2-(Trifluoromethyl)benzohydrazide
CAS Number

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Basic Information

Molecular Formula
C8H7F3N2O
Molecular Weight
204.15 g/mol

Physical Properties

Melting Point
132 °C

Chemical Identifiers

SMILES
C1=CC=C(C(=C1)C(=O)NN)C(F)(F)F
InChIKey
NTWTYYSQPAYEAE-UHFFFAOYSA-N

Database References

MDL Number
MFCD00221473

FAQ

2-(Trifluoromethyl)benzohydrazide has a crystalline form and a molecular weight of approximately 264.12 g/mol. It is slightly soluble in water and ethanol. This compound is known for its high reactivity, particularly towards nucleophiles and electrophiles, making it useful in various chemical transformations.
2-(Trifluoromethyl)benzohydrazide is typically synthesized by the condensation of 2-(trifluoromethyl)benzaldehyde with hydrazine hydrate. The reaction proceeds under mild conditions and yields a product that is isolated by recrystallization from an appropriate solvent.
2-(Trifluoromethyl)benzohydrazide is used in various industries, including pharmaceuticals, where it serves as a precursor for drug synthesis, and in polymer science, where it can be used as a functional monomer. It is also utilized in the development of sensors and as a precursor for semiconductor materials.
When handling 2-(Trifluoromethyl)benzohydrazide, it is important to use appropriate personal protective equipment (PPE) such as gloves and safety glasses. This compound should be used in a well-ventilated area or a fume hood to minimize inhalation risks. In case of a spill, it should be cleaned up carefully according to standard laboratory procedures, and an SDS (Safety Data Sheet) should be consulted for detailed guidelines.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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