4-Benzylidene-2-methyloxazol-5(4H)-one(CAS: 881-90-3)

4-Benzylidene-2-methyloxazol-5(4H)-one (CAS: 881-90-3) is a crystalline solid with a molecular weight of approximately 198.21 g/mol. It has low solubility in water but is more soluble in organic solvents like ethanol and acetone. This compound is known for its reactivity, particularly in forming complexes with metal ions and undergoing nucleophilic substitution reactions.

4-Benzylidene-2-methyloxazol-5(4H)-one can be synthesized by the condensation of 2-methyl-5-oxazoline-4-one with benzaldehyde in the presence of a strong base like sodium hydroxide. The reaction typically yields 90% purity with good selectivity and a high yield of 85%.

4-Benzylidene-2-methyloxazol-5(4H)-one (CAS: 881-90-3) is utilized in the pharmaceutical industry for the synthesis of certain drugs, in polymer chemistry for its use as a monomer, and in the production of sensors due to its reactivity with various functional groups. It is also explored in semiconductor applications for its electronic properties.

When handling 4-Benzylidene-2-methyloxazol-5(4H)-one (CAS: 881-90-3), it is recommended to wear appropriate personal protective equipment (PPE) such as gloves and goggles. The compound should be stored in a cool, dry place, away from direct sunlight and heat sources. In case of a spill, ensure proper ventilation and follow standard spill procedures as outlined in the safety data sheet (SDS). Always use a fume hood during handling to minimize inhalation exposure.