Ethyl 4-amino-2-pyrimidinecarboxylate(CAS: 71470-41-2)

Ethyl 4-amino-2-pyrimidinecarboxylate (CAS: 71470-41-2) is a crystalline solid with a molecular weight of approximately 184.18 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and acetonitrile. The compound is generally stable, but it can undergo hydrolysis in basic conditions. It shows moderate reactivity towards nucleophiles.

Ethyl 4-amino-2-pyrimidinecarboxylate is typically synthesized via the reaction of ethyl 2-pyrimidinecarboxylate with an amine, such as ethylamine, in the presence of a base like potassium carbonate. The reaction proceeds via nucleophilic substitution, yielding the desired amino compound with high selectivity and yield.

Ethyl 4-amino-2-pyrimidinecarboxylate (CAS: 71470-41-2) is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also utilized in the polymer industry for certain functional polymers, and in the sensor industry for the development of chemical sensors.

When handling Ethyl 4-amino-2-pyrimidinecarboxylate (CAS: 71470-41-2), ensure to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Store the compound in a cool, dry place away from sources of heat and direct sunlight. Disposal should follow local regulations, and spills should be handled according to the Material Safety Data Sheet (MSDS). Always work under a fume hood and consult the SDS for detailed safety information.