2-(4-Bromophenyl)pyrimidine(CAS: 210354-17-9)

2-(4-Bromophenyl)pyrimidine is a crystalline solid with a molecular weight of approximately 255.02 g/mol. It has a low solubility in water but is more soluble in organic solvents such as dichloromethane and ethyl acetate. This compound is not highly reactive under normal conditions but can undergo substitution reactions. It is used in the synthesis of pharmaceuticals and other organic compounds.

2-(4-Bromophenyl)pyrimidine is typically synthesized by the reaction of 4-bromophenylhydrazine with 2-chloropyrimidine. This process involves a classical condensation reaction under basic conditions. The yield can vary, but the method is straightforward and widely used in academic and industrial settings.

2-(4-Bromophenyl)pyrimidine is primarily used in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients. It also finds applications in the polymer industry for the development of new materials with specific properties. Additionally, it is utilized in the production of sensors and semiconductors due to its unique chemical and physical properties.

When handling 2-(4-Bromophenyl)pyrimidine, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate chemicals. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.