Ampicillin EP Impurity E(CAS: 1207726-28-0)

Ampicillin EP Impurity E (CAS: 1207726-28-0) is a white to off-white crystalline powder. It has a molecular weight of approximately 465.54 g/mol. The compound is slightly soluble in water and practically insoluble in ethanol. Chemically, it is a derivative of ampicillin, and exhibits similar reactivity with common nucleophiles and bases. It shows weak to moderate acidity and can undergo hydrolysis under acidic conditions.

Ampicillin EP Impurity E (CAS: 1207726-28-0) is synthesized through the hydrolysis of ampicillin. This involves treating ampicillin with an aqueous base, such as sodium hydroxide, to produce the desired impurity. The reaction is selective and yields high purity of the impurity, which is then purified by techniques such as recrystallization or chromatography.

Ampicillin EP Impurity E (CAS: 1207726-28-0) is primarily used in the pharmaceutical industry, particularly in the production of ampicillin and related antibiotics. It may also have applications in the research of antibiotic resistance mechanisms and in quality control checks for ampicillin and other beta-lactam antibiotics.

When handling Ampicillin EP Impurity E (CAS: 1207726-28-0), it is important to use personal protective equipment such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using caution, and the appropriate safety data sheet (SDS) should be referenced for specific handling instructions. Proper disposal procedures should be followed to ensure environmental safety.