2-Amino-5-fluorobenzenethiol(CAS: 33264-82-3)

2-Amino-5-fluorobenzenethiol (CAS: 33264-82-3) is a white crystalline solid with a molecular weight of approximately 179.04 g/mol. It is sparingly soluble in water but more soluble in organic solvents like ethanol and acetone. This compound is known for its reactivity, particularly towards electrophilic aromatic substitution reactions.

2-Amino-5-fluorobenzenethiol is typically synthesized through a multi-step process involving the fluorination of benzenethiol, followed by alkylation or acylation to introduce the amino group. Common catalysts include Lewis acids, and the reaction often requires the use of organic solvents at elevated temperatures.

2-Amino-5-fluorobenzenethiol (CAS: 33264-82-3) is used in various industries, including pharmaceuticals for drug synthesis, polymer science for functional monomers, and chemical sensing for the development of advanced sensors and semiconductors.

When handling 2-Amino-5-fluorobenzenethiol (CAS: 33264-82-3), proper personal protective equipment (PPE) should be worn, including gloves, goggles, and lab coats. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed safety instructions.