2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride(CAS: 85293-16-9)

2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9) is a white crystalline solid with a molecular weight of approximately 308.82 g/mol. It is highly soluble in water and ethanol but less soluble in organic solvents. This compound exhibits low reactivity in neutral and basic media, making it suitable for use in various chemical reactions. It has a pKa of around 4.5, indicating its basic nature.

2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9) is typically synthesized via the reaction of 2-(2-chloroethoxy)-ethanol with piperazine in the presence of a base such as sodium hydroxide. The reaction proceeds under mild conditions, and the yield can be up to 90%. The use of a suitable catalyst can improve the selectivity and efficiency of the reaction.

2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9) is used in the pharmaceutical industry for the synthesis of various drugs due to its basic properties. It is also applied in the polymer industry for the modification of polymer properties and in the semiconductor industry for use in chemical vapor deposition processes. Additionally, it has potential applications in sensor technology for the detection of specific chemicals.

When handling 2-(2-(Piperazin-1-yl)ethoxy)-ethanol dihydrochloride (CAS: 85293-16-9), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly rinsed with water. Always consult the Safety Data Sheet (SDS) for detailed emergency procedures and storage recommendations.