Methyl 3-amino-5-ethoxybenzoate(CAS: 706792-04-3)

Methyl 3-amino-5-ethoxybenzoate has a crystalline form. Its molecular weight is approximately 220.28 g/mol. It is slightly soluble in water but highly soluble in organic solvents like ethanol and acetone. This compound is reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal conditions but should be stored in a dry place to avoid hydrolysis.

Methyl 3-amino-5-ethoxybenzoate is typically synthesized by the reaction of 3-amino-5-ethoxybenzoic acid with methanol in the presence of a strong acid catalyst like trifluoroacetic acid. The yield is around 85%, and the reaction is highly selective. The product can be isolated by recrystallization from hot ethanol.

Methyl 3-amino-5-ethoxybenzoate is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry as a monomer and in the sensor industry for its electrochemical properties. Additionally, it has applications in semiconductor manufacturing due to its reactivity and stability.

When handling Methyl 3-amino-5-ethoxybenzoate, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Fume hoods should be used during the handling and synthesis of this compound. Spills should be cleaned up immediately using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for further details on safe handling and disposal.