5-ethoxypyrazin-2-amine(CAS: 647843-58-1)

5-Ethoxypyrazin-2-amine (CAS: 647843-58-1) is a crystalline solid with a molecular weight of approximately 124.16 g/mol. It has a low solubility in water (1.5 g/L at 20°C) and is moderately soluble in ethanol. This amine shows basic reactivity and can undergo nucleophilic substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place to avoid degradation.

5-Ethoxypyrazin-2-amine is typically synthesized by reacting ethylamine with pyrazin-2-carbaldehyde in the presence of sodium hydroxide. The reaction yields 5-ethoxypyrazin-2-amine with good selectivity and high yield. The product is isolated by filtration and can be purified by recrystallization from ethanol.

5-Ethoxypyrazin-2-amine (CAS: 647843-58-1) is used in the pharmaceutical industry as a precursor for the synthesis of various biologically active compounds. It also finds applications in the sensor industry for its ability to detect certain gases and in the semiconductor industry as a dopant material.

When handling 5-ethoxypyrazin-2-amine (CAS: 647843-58-1), appropriate personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a laboratory coat. The material should be stored in a cool, dry place, and all spills should be cleaned up using appropriate techniques. Handling should be done in a well-ventilated area or a fume hood to avoid inhalation. Always refer to the Safety Data Sheet (SDS) for detailed safety information.