Methyl 4-chloro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate(CAS: 688357-19-9)

Methyl 4-chloro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate (CAS: 688357-19-9) is a crystalline solid with a molecular weight of approximately 233.59 g/mol. It is poorly soluble in water but soluble in organic solvents such as methanol and acetonitrile. Chemically, it is reactive and can undergo substitution reactions and condensation reactions. This compound has a melting point of around 150°C and is stable under normal laboratory conditions.

Methyl 4-chloro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate (CAS: 688357-19-9) is typically synthesized via a condensation reaction of methyl 2-chloro-4-pyridinecarboxylate with 1H-pyrrolo[3,2-c]pyridine. The reaction involves the use of a dehydrating agent such as phosphorus oxychloride to promote the reaction. The yield is usually around 75-80%, and the product is isolated by recrystallization.

Methyl 4-chloro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate (CAS: 688357-19-9) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the production of organic semiconductors and other chemical intermediates. This compound can be a valuable intermediate in the development of innovative materials for electronics and sensors.

When handling Methyl 4-chloro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate (CAS: 688357-19-9), proper personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.