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2-hydroxy-1,2-bis(4-methoxyphenyl)ethan-1-one(CAS: 119-52-8)

2-hydroxy-1,2-bis(4-methoxyphenyl)ethan-1-one
CAS Number

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Basic Information

Molecular Formula
C16H16O4
Molecular Weight
272.3 g/mol
Physical State
Powder

Physical Properties

Melting Point
110.0 to 113.0 deg-C
Boiling Point
459.3°C at 760 mmHg
Flash Point
171 ºC
Water Solubility
Soluble in water, ethanol and acetone.

Chemical Identifiers

SMILES
COC1=CC=C(C=C1)C(C(=O)C2=CC=C(C=C2)OC)O
InChIKey
LRRQSCPPOIUNGX-UHFFFAOYSA-N

Database References

MDL Number
MFCD00008411
Beilstein Registry Number
3211892

FAQ

2-hydroxy-1,2-bis(4-methoxyphenyl)ethan-1-one (CAS: 119-52-8) is a crystalline solid with a molecular weight of approximately 328.34 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and dichloromethane. Chemically, it is relatively stable under normal conditions but can react with strong bases to produce methoxy derivatives.
2-hydroxy-1,2-bis(4-methoxyphenyl)ethan-1-one (CAS: 119-52-8) is commonly synthesized via the condensation of 4-methoxybenzaldehyde with phenylacetic acid. The reaction is catalyzed by a strong acid like hydrochloric acid, and the yield is typically around 70-80%. The product is purified by recrystallization from a suitable solvent.
2-hydroxy-1,2-bis(4-methoxyphenyl)ethan-1-one (CAS: 119-52-8) is used in the pharmaceutical industry for intermediates in drug synthesis, in the polymer industry for modifying properties of polymers, and in the semiconductor industry for organic semiconductor materials. It also finds applications in sensor technology and as a precursor for dyes.
Precautions include using appropriate personal protective equipment (PPE) such as gloves and goggles. It should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions. Storage should be in a cool, dry place away from direct sunlight and flammable materials.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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