4-Ethyl-D-phenylalanine(CAS: 721385-17-7)

4-Ethyl-D-phenylalanine is a white crystalline solid with a molecular weight of approximately 186.25 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. Chemically, it is an amino acid derivative known for its reactivity in peptide synthesis and its hydrolytic stability under neutral conditions.

4-Ethyl-D-phenylalanine is typically synthesized through a condensation reaction between D-phenylalanine and ethyl chloroformate, catalyzed by a suitable base like triethylamine. The reaction involves a standard peptide coupling protocol, leading to a high yield of the desired product with good stereoselectivity.

4-Ethyl-D-phenylalanine is primarily used in the pharmaceutical industry for the development of peptide-based drugs. It is also utilized in the chemical industry for the synthesis of various peptides and in the food industry as a flavor enhancer. Additionally, it can be found in research applications where its unique properties make it suitable for specific studies.

When handling 4-Ethyl-D-phenylalanine, it is important to use appropriate personal protective equipment (PPE) such as gloves and goggles. The material should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, handle it in a well-ventilated area and follow standard chemical spill procedures. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.