3-Bromo-2,6-difluoroaniline(CAS: 1262198-07-1)

3-Bromo-2,6-difluoroaniline is a white crystalline solid with a molecular weight of approximately 245.01 g/mol. It has a low water solubility and is slightly soluble in common organic solvents. It is moderately reactive and can undergo substitution reactions. It is commonly used in organic synthesis as a functional group for further derivatization.

3-Bromo-2,6-difluoroaniline is typically synthesized via the bromination of 2,6-difluoroaniline using N-bromosuccinimide (NBS) in the presence of a radical initiator such as AIBN. The reaction yields a high degree of selectivity and good yield, making it a reliable method for industrial production.

3-Bromo-2,6-difluoroaniline is primarily used in the pharmaceutical industry for the synthesis of intermediates and drugs. It is also used in the polymer industry, where it serves as a monomer for the production of high-performance polymers. Additionally, it has applications in the sensor industry for the development of chemical sensors and in the semiconductor industry for certain purification processes.

3-Bromo-2,6-difluoroaniline should be handled in a chemical fume hood to minimize exposure to vapors. Protective equipment such as safety goggles, gloves, and a lab coat is recommended. Spills should be disposed of according to local regulations, and emergency response procedures should be followed. A Safety Data Sheet (SDS) should be consulted for detailed handling and storage information.