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Dasatinib-d8(CAS: 1132093-70-9)

Dasatinib-d8
CAS Number

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Basic Information

Molecular Formula
C22H18ClD8N7O2S
Molecular Weight
496.07 g/mol

Physical Properties

Melting Point
272-274°C

Chemical Identifiers

SMILES
OCCN1C([2H])([2H])C([2H])([2H])N(C(C1([2H])[2H])([2H])[2H])c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl
InChIKey
ZBNZXTGUTAYRHI-COMRDEPKSA-N

Database References

MDL Number
MFCD15071210

FAQ

Dasatinib-d8 (CAS: 1132093-70-9) is regulated under GHS classification as a hazardous chemical. In the European Union, it is covered by REACH regulations, which require manufacturers to register substances above one tonne per year. FDA and EPA have specific guidelines for the import, production, and use of this compound in pharmaceuticals and research.
Alternative reagents such as dasatinib-d4 and dasatinib-d6 are used as isotopically labeled analogs. Isomers like cis-dasatinib and trans-dasatinib may also be considered. Synthesizers often explore these options to achieve similar labeling or structural modifications.
The market for Dasatinib-d8 (CAS: 1132093-70-9) is growing due to its use in pharmaceutical research, particularly in studying the metabolism and pharmacokinetics of dasatinib. Recent trends show an increase in demand for isotopically labeled compounds to enhance drug development and safety assessments.
Waste containing Dasatinib-d8 (CAS: 1132093-70-9) should be collected in a sealed, leak-proof container and disposed of through a licensed hazardous waste management facility. Incineration is a common method, and environmental protection precautions must be followed to prevent contamination of soil and water.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

Contact Person

Xu Jianmei

Email

1490673506@qq.com

Mobile

19108750708

Telephone

8621-3650126

Address

No. 202, 2nd Floor, Building 8, Huimin Road 1871, Minhang District, Shanghai