2-Amino-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one(CAS: 1367369-77-4)

2-Amino-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one is a white crystalline solid with a molecular weight of approximately 409.4 g/mol. It is slightly soluble in water and ethanol. The compound is reactive towards bases and can undergo hydrolysis under basic conditions. It is stable under normal storage conditions but should be protected from moisture and light.

2-Amino-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one is typically synthesized via a multi-step process involving the reaction of a cyclopentene derivative with a guanidine compound. The reaction involves the use of a catalytic amount of a strong base, such as sodium hydride, and is performed in an anhydrous solvent like dimethylformamide. The yield is moderate to high, depending on the purity of the starting materials and reaction conditions.

2-Amino-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It also has potential applications in the polymer industry for the development of new materials with tailored properties. Additionally, it may be used in the sensor and semiconductor industries for specialized applications such as gas sensors and electronic devices.

When handling 2-Amino-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro-6H-purin-6-one, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or under a fume hood. Spills should be immediately cleaned up using absorbent materials and the affected area should be flushed with water. The safety data sheet (SDS) should be consulted for detailed emergency procedures and storage instructions.