Benzyl 2-methyl-4-oxo-1-piperidinecarboxylate(CAS: 849928-34-3)

Benzyl 2-methyl-4-oxo-1-piperidinecarboxylate is a white crystalline powder with a molecular weight of approximately 250.35 g/mol. It is sparingly soluble in water but soluble in common organic solvents like ethanol and acetone. The compound is moderately reactive towards nucleophiles and can undergo ester hydrolysis under basic conditions. It has low volatility and a melting point of around 120-122°C.

Benzyl 2-methyl-4-oxo-1-piperidinecarboxylate can be synthesized via the reaction of benzyl chloride with 2-methyl-4-oxo-1-piperidinecarboxylic acid. The synthesis typically involves the use of a base like triethylamine to facilitate the nucleophilic substitution reaction. The product is isolated by filtration and recrystallization from ethanol, yielding a white crystalline solid with high purity.

Benzyl 2-methyl-4-oxo-1-piperidinecarboxylate is primarily used in the pharmaceutical industry for the synthesis of various drugs. It also finds applications in the polymer industry as a monomer for the production of polymers with specific properties. Additionally, it is used in the development of sensors and semiconductors due to its unique chemical functionality.

When handling Benzyl 2-methyl-4-oxo-1-piperidinecarboxylate, it is important to wear appropriate personal protective equipment (PPE) including gloves and safety goggles. This compound should be handled in a well-ventilated area or a fume hood due to its reactivity. In case of a spill, it should be carefully cleaned up using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.