2-(3-Chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one(CAS: 90-31-3)

2-(3-Chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one is a crystalline solid with a molecular weight of approximately 220.01 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. This compound is relatively stable under normal conditions but can react with strong bases to form pyrazoles. It is used in various synthetic reactions due to its reactivity and functional groups.

2-(3-Chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one is synthesized via a multistep process involving the reaction of 2,4-dichloro-3-(3-chlorophenyl)pyrazole with methylamine. This reaction is typically catalyzed by a base such as potassium hydroxide, and the yield is moderate to good. The reaction is carried out under mild conditions to maintain the structural integrity of the pyrazole ring.

2-(3-Chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one is used in the pharmaceutical industry for the synthesis of drugs with antimicrobial properties. It is also utilized in the chemical industry for the production of certain polymers and sensors. Additionally, this compound has applications in the semiconductor industry due to its unique electronic properties.

When handling 2-(3-Chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one, appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn. This compound should be stored in a cool, dry place away from direct sunlight. If a spill occurs, it should be handled in a fume hood, and the area should be well-ventilated. Safety data sheets (SDS) should be consulted for detailed emergency procedures and handling guidelines.