1-Fluoro-3-iodo-5-methylbenzene(CAS: 491862-84-1)

1-Fluoro-3-iodo-5-methylbenzene (CAS: 491862-84-1) is a crystalline solid with a molecular weight of approximately 264.9 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetonitrile. The compound is relatively unreactive under normal conditions but can undergo substitution reactions under appropriate conditions. It has a high melting point and is typically stable under standard laboratory conditions.

1-Fluoro-3-iodo-5-methylbenzene (CAS: 491862-84-1) is typically synthesized via a fluorination and iodination process. The starting material, 5-methylbenzofluoride, is treated with iodine in the presence of a Lewis acid catalyst such as aluminum chloride to form the intermediate. Further treatment with other reagents leads to the final product. The overall process yields up to 90% of the target compound, with good selectivity and purity.

1-Fluoro-3-iodo-5-methylbenzene (CAS: 491862-84-1) is used in the pharmaceutical industry for the synthesis of certain drugs due to its unique structural properties. It is also utilized in the polymer industry for the development of specialized materials with specific functionalities. Additionally, it has potential applications in the field of sensors and semiconductors, although its primary use remains in the pharmaceutical sector.

When handling 1-Fluoro-3-iodo-5-methylbenzene (CAS: 491862-84-1), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood due to its potential for inhalation hazards. Handling should be done with care to avoid skin contact. In the event of a spill, ensure proper containment and disposal according to safety data sheet (SDS) guidelines. Always refer to the latest SDS for detailed safety instructions.