Compound Q&A

How is 1-Fluoro-3-iodo-5-methylbenzene (CAS: 491862-84-1) typically synthesized?

Answer

1-Fluoro-3-iodo-5-methylbenzene
1-Fluoro-3-iodo-5-methylbenzene (CAS: 491862-84-1) is typically synthesized via a fluorination and iodination process. The starting material, 5-methylbenzofluoride, is treated with iodine in the presence of a Lewis acid catalyst such as aluminum chloride to form the intermediate. Further treatment with other reagents leads to the final product. The overall process yields up to 90% of the target compound, with good selectivity and purity.

About

English Name 1-Fluoro-3-iodo-5-methylbenzene
Molecular Formula C7H6FI
Molecular Weight 236.027 g/mol
SMILES CC1=CC(=CC(=C1)I)F
InChIKey OIYMMFUTIUURQT-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55

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