3-(3,4-Difluorophenyl)-3-oxopropanenitrile(CAS: 71682-97-8)

3-(3,4-Difluorophenyl)-3-oxopropanenitrile (CAS: 71682-97-8) is a white crystalline solid. It has a molecular weight of approximately 183.06 g/mol and is slightly soluble in water. The compound is reactive towards nucleophiles and can undergo addition reactions. It is stable under normal conditions but should be stored in a cool, dark place away from direct sunlight.

3-(3,4-Difluorophenyl)-3-oxopropanenitrile is typically synthesized via the reaction of 3-(3,4-difluorophenyl)propionitrile with a base. Commonly, this involves the use of sodium hydride as a base. The reaction is performed under anhydrous conditions and requires careful handling to avoid decomposition. The product is isolated by vacuum distillation or crystallization.

3-(3,4-Difluorophenyl)-3-oxopropanenitrile is primarily used in the pharmaceutical industry as an intermediate for drug synthesis. It is also used in the polymer industry for the development of high-performance materials and in the semiconductor industry for electronic applications. Additionally, it has potential applications in the sensor industry due to its chemical reactivity.

When handling 3-(3,4-Difluorophenyl)-3-oxopropanenitrile (CAS: 71682-97-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be handled in a well-ventilated fume hood to avoid inhalation. In case of a spill, it should be cleaned up using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.