4-(Benzyloxy)-4-oxobutanoic acid(CAS: 103-40-2)

4-(Benzyloxy)-4-oxobutanoic acid is a white crystalline solid with a molecular weight of 212.23 g/mol. It has low water solubility and good solubility in organic solvents such as ethanol and acetone. The compound is relatively stable under normal conditions but can react with strong bases and oxidizing agents. It has a pKa around 4.2.

4-(Benzyloxy)-4-oxobutanoic acid is typically synthesized via the condensation of benzyloxyacetic acid and acetic anhydride. The reaction is catalyzed by a strong acid like sulfuric acid, and it yields 95% pure product with good selectivity. The reaction is carried out in anhydrous conditions to prevent hydrolysis.

4-(Benzyloxy)-4-oxobutanoic acid is used in the pharmaceutical industry as a precursor for the synthesis of various bioactive compounds. It is also utilized in the polymer industry for modifying the properties of polymers. Additionally, it has applications in the sensor and semiconductor industries due to its reactivity and stability.

When handling 4-(Benzyloxy)-4-oxobutanoic acid, it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. It should be stored in a cool, dry place away from heat sources and oxidizing agents. In case of spill, the area should be well-ventilated and the spill cleaned up using absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.