(3S)-3-Amino-3-(3-nitrophenyl)propanoic acid(CAS: 734529-57-8)

(3S)-3-Amino-3-(3-nitrophenyl)propanoic acid is a white crystalline solid with a molecular weight of approximately 218.08 g/mol. It has a solubility of about 0.1 g/100 mL in water at 25°C. This compound exhibits moderate reactivity, particularly towards nucleophilic substitution reactions and acid/base catalysis. It is stable under normal storage conditions but should be stored in a cool, dry place away from direct sunlight to prevent degradation.

(3S)-3-Amino-3-(3-nitrophenyl)propanoic acid can be synthesized by the condensation of 3-nitrobenzaldehyde with 3-aminopropanoyl chloride in the presence of an acid catalyst such as sulfuric acid. The reaction typically proceeds with good yield and selectivity. The product can be purified by recrystallization from appropriate solvents to achieve high purity.

(3S)-3-Amino-3-(3-nitrophenyl)propanoic acid is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also applicable in the chemical industry for polymer synthesis and as a component in the development of sensors and semiconductors. Its specific applications in these sectors are dependent on its unique chemical properties and reactivity.

When handling (3S)-3-Amino-3-(3-nitrophenyl)propanoic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coat. This compound should be handled in a well-ventilated area or a fume hood to minimize exposure to airborne particles. Spills should be cleaned up immediately using appropriate absorbent materials and disposed of according to safety data sheet (SDS) guidelines. The SDS should be consulted for detailed handling and storage instructions.