2-Bromo-5-chlorobenzaldehyde(CAS: 174265-12-4)

2-Bromo-5-chlorobenzaldehyde (CAS: 174265-12-4) is a crystalline solid with a molecular weight of approximately 227.02 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive, showing both electrophilic aromatic substitution and nucleophilic addition reactivity. It is commonly used in organic synthesis as a functionalized benzaldehyde derivative.

2-Bromo-5-chlorobenzaldehyde (CAS: 174265-12-4) can be synthesized via the bromination and chlorination of benzaldehyde followed by coupling reactions. Common methods include the sequential use of brominating agents like N-bromosuccinimide (NBS) and chlorinating agents such as thionyl chloride (SOCl2). This process requires careful control of reaction conditions to achieve high selectivity and yield.

2-Bromo-5-chlorobenzaldehyde (CAS: 174265-12-4) is used in various industries, including pharmaceuticals for the synthesis of intermediates, polymers for functionalizing polymer chains, and sensors for detecting specific chemical species. It also finds application in semiconductor manufacturing for modifying surface properties.

When handling 2-Bromo-5-chlorobenzaldehyde (CAS: 174265-12-4), it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up carefully using appropriate absorbents, and the area should be well ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.