2-(2-Nitrophenyl)ethanamine hydrochloride (1:1)(CAS: 861337-74-8)

2-(2-Nitrophenyl)ethanamine hydrochloride (CAS: 861337-74-8) is a crystalline solid with a molecular weight of approximately 231.07 g/mol. It has a pKa of about 1.5 and is highly soluble in water. The compound is moderately reactive, particularly with strong bases and reducing agents. It exhibits good solubility in organic solvents such as methanol and ethanol, but has limited solubility in non-polar solvents.

2-(2-Nitrophenyl)ethanamine hydrochloride is synthesized through a multi-step process involving the reaction of 2-nitrophenylamine with hydrochloric acid. The key steps include the formation of the amine from the nitro group, followed by the protonation of the amine to form the hydrochloride salt. This reaction is typically carried out in an aqueous medium, with careful control of pH and temperature to ensure selectivity.

2-(2-Nitrophenyl)ethanamine hydrochloride (CAS: 861337-74-8) is primarily used in the pharmaceutical industry for its role as a precursor in the synthesis of various pharmaceutical compounds. It also finds applications in the polymer industry, where it serves as a component in certain polymer formulations. Additionally, it is utilized in the development of sensors and semiconductors for its unique chemical properties.

When handling 2-(2-Nitrophenyl)ethanamine hydrochloride (CAS: 861337-74-8), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to vapors. Spills should be cleaned up using an appropriate absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.